代雪艷

個人簡介

代雪艷（1993.10），漢族，河南周口人，博士，副教授（校聘），碩士研究生導師，入選贛鄱俊才支持計劃·青年科技人才。主要從事畜禽營養(yǎng)代謝病與中毒病及小動物（犬、貓等）疾病防控研究。現(xiàn)為中國畜牧獸醫(yī)學會犬學分會理事，江西省省級農(nóng)業(yè)科技特派員，江西省陸生野生動物疫源疫病防控專家，江西省畜牧獸醫(yī)學會理事，江西省寵物診療協(xié)會常務理事，江西省上栗兔產(chǎn)業(yè)科技小院指導專家。主持國家和省部級項目5項，行業(yè)專項2項。以第一作者或通訊作者在Journal of Hazardous Materials、Science of the Total Environment、Journal of Agricultural and Food Chemistry、Food & Function等期刊發(fā)表高水平學術(shù)論文20余篇，其中一區(qū)Top期刊10余篇，ESI前1%高被引及期刊封面論文4篇。授權(quán)專利5件，軟件著作權(quán)9項。參編著作1部。

教育經(jīng)歷：

2012/09-2016/07，天津農(nóng)學院，動物醫(yī)學，本科，學士

2016/09-2019/07，江西農(nóng)業(yè)大學，臨床獸醫(yī)學，研究生，碩士

2019/09-2022/06，東北農(nóng)業(yè)大學，臨床獸醫(yī)學，研究生，博士

工作經(jīng)歷：

2022/07-至今，江西農(nóng)業(yè)大學動物科技術(shù)院，講師

近幾年主持的科研項目：

（1）國家自然科學基金青年項目，BMP4介導的線粒體自噬在鄰苯二甲酸二（2-乙基）己酯致雞胚神經(jīng)嵴損傷種的作用（32302952），2024/01-2026/12，主持，在研。

（2）贛鄱俊才支持計劃 青年科技人才托舉項目，AMPK-ULK1 軸介導的鐵自噬在鄰苯二甲酸二（2-乙基）己酯誘導雞胚神經(jīng)嵴細胞鐵死亡中的作用（2024QT12），2024/06-202705，主持，在研。

（3）江西省自然科學基金青年項目，SIRT3介導的Akt-依賴性鐵死亡在DEHP暴露抑制雞胚神經(jīng)嵴上皮-間質(zhì)細胞轉(zhuǎn)化過程中的作用（20232BAB215058），2023/07-2026/07，主持，在研。

（4）江西省教育廳教改項目，《小動物疾病學》線上線下混合課堂教學模式的探索與實踐，2023/12-2025/12，主持，在研。

（5）江西省教育廳科技計劃一般項目，線粒體健康調(diào)控在BMP4介導鎘致雞胚顱面部神經(jīng)嵴毒性中的作用，2023/01-2025/12，主持，在研。

（6）橫向項目：低聚原花青素對肥育豬生長性能及豬肉品質(zhì)的影響，2022/12-2024/12，主持，在研。

（7）橫向項目：堿性礦物質(zhì)復合物飼料添加劑對綿羊生長性能及肉品質(zhì)的影響，2023/10-2025/10，主持，在研。

近幾年發(fā)表的論文（第一作者或通訊作者文章）：

[1] Xueyan Dai^#, Xiaowei Li, Shiyong Zhu, Muzi Li, Yi Zhao, Milton Talukder, Yanhua Li, Jinlong Li^*. Lycopene Ameliorates Di(2-ethylhexyl) Phthalate-Induced Pyroptosis in Spleen via Suppression of Classic Caspase-1/NLRP3 Pathway. Journal of Agricultural and Food Chemistry. 2021, 69:1291-1299 (IF₂₀₂₁: 5.714，中科院大類一區(qū)TOP，ESI高被引及封面文章，第一作者)

[2] Xueyan Dai^#, Jian Chen, Shiyong Zhu, Muzi Li, Yi Zhao, Milton Talukder, Jinlong Li^*. Role of toll-like receptor (TLR)/MyD88 signaling in lycopene alleviated di-(2-ethylhexyl) phthalate (DEHP)-induced inflammatory response in spleen. Journal of Agricultural and Food Chemistry, 2022, 70:10022-10030. (IF₂₀₂₁: 5.714，中科院大類一區(qū)TOP，ESI高被引文章，第一作者)

[3] Xueyan Dai^#, Yi Zhao, Jing Ge, Shiyong Zhu, Muzi Li, Milton Talukder, Jinlong Li^*. Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway [J]. Food & Function, 2021, 12:4582-4590. (IF₂₀₂₁: 6.317，中科院大類一區(qū)，ESI高被引文章，第一作者)

[4] Xueyan Dai^#, Shiyong Zhu, Jian Chen, Muzi Li, Yi Zhao, Milton Talukder, Jinlong Li^*. Lycopene alleviates di(2-ethylhexyl) phthalate-induced oxygen species production via activating the P62-Keap1-NRF2 signaling in mice spleen [J]. Food Chemical and Toxicology, 2022, 168:113324. (IF₂₀₂₁: 5.571，中科院小類一區(qū)，ESI高被引文章，第一作者)

[5] Xueyan Dai^#, Jia Lin, Shiyong Zhu, Jianying Guo, Jiagen Cui, Jinlong Li^*. Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene. Food Chemical and Toxicology. 2022（IF₂₀₂₁: 6.023，中科院小類一區(qū)，第一作者).

[6] Xueyan Dai^#, Chenghong Xing, Huabin Cao, Junrong Luo, Tiancheng Wang, Ping Liu, Xiaoquan Guo, Guoliang Hu, Caiying Zhang^*. Alterations of mitochondrial antioxidant indexes and apoptosis in duck livers caused by molybdenum or/and cadmium [J]. Chemosphere, 2018, 193:574-580. (IF₂₀₁₈: 5.108，中科院大類二區(qū)TOP，第一作者)

[7] Xueyan Dai^#, Gaohui Nie, Huabin Cao, Chenghong Xing, Guoliang Hu, Caiying Zhang^*. In vivo assessment of molybdenum and cadmium co-induced the mRNA levels of heat shock proteins, inflammatory cytokines and apoptosis in duck testicles [J]. Poultry Science, 2019, 0:1-8. (IF₂₀₁₉: 2.659，中科院大類二區(qū)TOP，第一作者)

[8] Xue-Yan Dai^# Shi-Yong Zhu^#, Mu-Zi Li, Milton Talukder, Yi Zhao, and Jin-Long Li* Potential Role of Lycopene in the Inhibition of Di(2-ethylhexyl) Phthalate-Induced Ferroptosis in Spleen Via Modulation of Iron Ion Homeostasis [J]. ACS Pharmacol Transl Sci. 2021, 27;4(1):386-395 (IF₂₀₂₂: 6.0，中科院大類二區(qū)TOP，第一作者)

[9] Jing Chen^#, Xueyan Dai^#, Chenghong Xing, Yike Zhang, Huabin Cao, Guoliang Hu, Xiaoquan Guo, Xiaona Gao, Ping Liu, Fan Yang^*. Cooperative application of transcriptomics and ceRNA hypothesis: lncRNA-00742/miR-116 targets CD74 to mediate vanadium-induced mitochondrial apoptosis in duck liver[J]. Journal of Hazardous Materials, 2024;135904. (IF₂₀₂₄: 12.200，中科院大類一區(qū)TOP，共第一作者)

[10] Hang Liu^#, Xueyan Dai^#, Shiwen Xu, Huiling Guo, Jiamei Zhu, Sunan Wang, Yuning Wu, Caiying Zhang. Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium [J]. Science of the Total Environment, 902 (2023) 166074 (IF₂₀₂₃: 10.754，中科院大類一區(qū)TOP，共第一作者)

[11] Muzi Li^#, Xueyan Dai ^#, Yingxin Zhao, Xiaowei Li, Yi Zhao, Jinlong Li^* Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitochondrial damage and inflammation in kidney via cGAS?STING signaling [J]. Journal of Agricultural and Food Chemistry, 2023, 71(1):569-579. (IF₂₀₂₁: 5.714，中科院大類一區(qū)TOP，共第一作者)

[12] Jiamei Zhu^#, Xueyan Dai^#, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, and Caiying Zhang^*. Molybdenum and cadmium co induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anasplatyrhyncha) testes [J]. Poultry Science, 2024, 103:103653. (IF₂₀₂₄: 4.4，中科院大類一區(qū)TOP，共第一作者)

[13] Ting Cui^#, Xueyan Dai^#, Huiling Guo, Dianyun Wang, Bingyan Huang, Wenjing Pu, Xuesheng Chu, Caiying Zhang^*. Molybdenum and cadmium co-induce necroptosis through Th1/Th2 imbalance-mediated endoplasmic reticulum stress in duck ovaries [J]. J Environ Sci. 2024; 142:92-102 (IF₂₀₂₄: 6.9，中科院大類二區(qū)，共第一作者)

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